JRS Mexico works closely with the Jesuit Migration Network and the Jesuit Migration Service to accompany migrants in need of international protection through legal and psychosocial support. JRS Mexico provides a variety of services including a shelter and emergency assistance, psychosocial support, community integration projects, recreational activities, and legal assistance. JRS Mexico also advocates for refugees and asylum seekers through awareness and visibility campaigns. 

JRS/USA and JRS/Mexico work closely together on the Binational Border Program. The priorities of the program aim to reduce suffering, improve mental health and psychosocial wellbeing, and the decrease of violations to the legal rights for refugees, asylum seekers, and other displaced people in the Cd. Juarez & El Paso region through the provision of information, support, and other legal and MHPSS services.